Simon at ThemeShift has released deFolio, a new WordPress portfolio theme. The new portfolio theme features a jQuery image slider, a number of shortcodes, and uses custom post types for portfolio content.
Simon describes the work that went into deFolio in his announcement post:
Creating this theme has been a lot work because it is so complex and flexible. Apart from the jQuery image sliders, that can display recent posts or portfolio items or image-only galleries, the deFolio home page is a huge widget area that can be personalized with a set of custom widgets. You control where the sidebar appears and what size the post thumbnails have (in general or post by post). Even the width of the post boxes are in your hands without touching any code.
Check out the deFolio theme demo, and if it works for you pick it up for 39€.